论文部分内容阅读
目的:动态分析某三甲医院肿瘤患者抗菌药物的使用情况,考察临床药师用药干预对合理使用抗菌药物的促进效果。方法:利用回顾性调查方法对某医院肿瘤患者抗菌药物使用情况进行动态分析。每月每个病区随机抽取使用抗菌药物的患者进行审核。应用PDCA循环管理对一病区抗菌药物使用的合理性进行干预。比较一病区和二病区抗菌药物的动态变化。结果:肿瘤内科一病区和二病区抗菌药物使用率分别为(6.3±1.5)%和(12.5±2.8)%(P<0.01)、抗菌药物费用占药费总额百分率分别为(1.6±1.2)%和(2.8±1.0)%(P<0.05);2个病区抗菌药物合理率分别为82.3%和66.6%(P<0.05)。不合理用药主要表现在用法用量不合理、无用药指征、用药级别高、特殊级抗菌药物无感染专科会诊单、越级使用抗菌药物。结论:老年肿瘤患者感染发病率较高,PDCA干预病区的抗菌药物使用率、使用强度、抗菌药物费用低于非干预病区。临床药师用药干预实践能够促进抗菌药物的合理使用。
Objective: To dynamically analyze the use of antimicrobial agents in cancer patients in a top three hospital and investigate the effects of intervention by pharmacists on rational use of antimicrobial agents. Methods: A retrospective survey was conducted to analyze the use of antimicrobial agents in cancer patients in a hospital. Patients are randomly selected for antibiotics from each ward on a monthly basis for review. Apply PDCA cycle management to interfere with the rationality of antimicrobial use in a ward. Compare the dynamic changes of antibacterials in one ward and two wards. Results: The antibacterials utilization rates in the first and second wards of the oncology were (6.3 ± 1.5)% and (12.5 ± 2.8)%, respectively (P <0.01) ) And (2.8 ± 1.0)% respectively (P <0.05). The reasonable rates of antibiotics in the two wards were 82.3% and 66.6%, respectively (P <0.05). Irrational use of drugs mainly in the amount of unreasonable usage, no indication of the use of drugs, high levels of medication, special grade antibacterial drugs without infection specialist consultation, the more leveled use of antimicrobial agents. Conclusion: The incidence of senile cancer patients is high, and the rate of using antibacterial drugs, the intensity of use and the cost of antibacterial drugs in PDCA intervention area are lower than those in non-intervention area. Clinical pharmacist interventions can promote the rational use of antimicrobial agents.