论文部分内容阅读
目的探讨2015年舟山某院就诊小儿人群EB病毒(epstein-barr virus,EBV)、巨细胞病毒(czytomegalovirus,CMV)、柯萨奇病毒(Coxsackievirus,Cox V)感染的分布特征。方法选取2015年1月-12月在本院门诊或住院小儿患者1 284例,抽取静脉血分离血清,采用化学发光法EBV VCA-Ig M、EBV EA-Ig A、EBV VCA-Ig A、CMV-Ig M,采用酶联免疫法检测Cox V-Ig M。结果总样本群中EBV VCA-Ig M检出阳性83例(6.46%),EBV EA-Ig A检出阳性23例(1.79%),EBV VCA-Ig A检出阳性52例(4.05%),CMV-Ig M检出阳性88例(6.85%),Cox V-Ig M检出阳性150例(11.68%)。4岁~7岁的Cox V-Ig M阳性率(15.86%)高于1岁~3岁组(10.56%)和8岁~12岁组(9.80%),差异有统计学意义(χ2值分别为5.95、3.95,P<0.05)。1岁~3岁组男性EBV VCA-Ig M阳性率(8.14%)高于女性(4.89%),差异有统计学意义(χ2=6.83,P<0.01)。结论应加强本地区4岁~7岁患儿的Cox V-Ig M及1岁~3岁组的男性患儿EBV VCA-Ig M的监测。
Objective To investigate the distribution of Epstein-Barr virus (EBV), cytomegalovirus (CMV) and Coxsackievirus (Cox V) infection in children from a hospital in Zhoushan in 2015. Methods A total of 1 284 outpatients or inpatients from January 2015 to December 2015 in our hospital were enrolled in this study. Serum samples were extracted from venous blood and analyzed by chemiluminescence immunoassay (EBV VCA-Ig M, EBV EA-Ig A, EBV VCA-Ig A, CMV -Ig M, Cox V-Ig M was detected by enzyme-linked immunosorbent assay. Results The positive rate of EBV VCA-Ig M was 83 (6.46%) in the total sample group, 23 (1.79%) were positive by EBV EA-Ig A, 52 (4.05%) were positive by EBV VCA- CMV-Ig M positive 88 cases (6.85%), Cox V-Ig M positive 150 cases (11.68%). The positive rate of Cox V-Ig M between the ages of 4 and 7 (15.86%) was higher than that of the patients aged 1 to 3 years old (10.56%) and the age group of 8 to 12 years old (9.80%), the difference was statistically significant 5.95, 3.95, P <0.05). The positive rate of EBV VCA-Ig M in male aged 1 to 3 years (8.14%) was higher than that of female (4.89%), the difference was statistically significant (χ2 = 6.83, P <0.01). Conclusion Cox V-Ig M in children aged 4 to 7 years and EBV VCA-Ig M in men aged 1 to 3 years in this region should be monitored.