对牙龈鳞癌的生物性活力估计,常将其分为高度分化、中度分化或分化较差。但肿瘤表面常为高度分化,而在戈浸润深部则分化较差;且对某一个体肿瘤的分化程度亦无精确的定义,不同程度的分化与预后的关系亦不显著。所以,在多数病人中,以此作为选择治疗的基础是不足的。因此,应寻求较客观的标准,以作牙龈的组织学分类,希能更确切地反映出肿瘤的生物学生长能力,借此改善病人的治疗及预后。根据这种新原则,最近对喉、腭及牙龈鳞癌 Estimates of the biological activity of gingival squamous cell carcinoma are often classified as highly differentiated, moderately differentiated, or poorly differentiated. However, the surface of the tumor is often highly differentiated and poorly differentiated in the deep part of the infiltrate. There is no precise definition of the degree of differentiation of an individual tumor, and the relationship between differentiation and prognosis is not significant. Therefore, in most patients, it is not sufficient to base this choice on treatment. Therefore, more objective criteria should be sought for the histological classification of the gums. It is hoped that this will more accurately reflect the biological growth capacity of tumors, thereby improving the patient’s treatment and prognosis. According to this new principle, squamous cell carcinoma of the larynx, gills and gums has recently been