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利凡诺注射液是广泛应用于中期妊娠引产的药物。我们原用0.1%硫代硫酸钠作抗氧剂,制备利凡诺水针剂,但在放置过程中不稳定,三个月后渐渐析出结晶,给制备带来了困难。我们根据吐温-80具有增溶、抗氧作用,用1%吐温-80代替硫代硫酸钠制备的注射液,在室温、避光放置,观察8个月未有结晶析出,并能保持原来颜色,用581-G型光电比色计,选
Rivanol injection is widely used in mid-term pregnancy induction of drugs. We originally used 0.1% sodium thiosulfate as an antioxidant to prepare Rivanol water injection, but it was not stable during the process of settling. Gradually crystallized after three months, which made it difficult to prepare. According to Tween-80 with solubilization, anti-oxygen effect, with 1% Tween -80 instead of sodium thiosulfate prepared injection, at room temperature, placed in the dark, observed in 8 months without crystallization, and can maintain The original color, with 581-G-type photoelectric colorimeter, election