【摘 要】
：
本文系统研究了绣球菌水提物对小鼠非特异性免疫功能及细胞免疫功能的影响.研究发现,绣球菌水提物300和600 mg·kg-1剂量灌胃给药15 d,对环磷酰胺诱导小鼠免疫下降具有一定的保护作用,可增强巨噬细胞的吞噬功能;体外试验结果表明,绣球菌水提物0.4和0.8 mg·mL-1单独或联合ConA(5μg·mL-1)用药均具有明显的促淋巴细胞增殖作用.上述结果表明,绣球菌水提物具有促进免疫功能的药效学作用.
【机 构】
：
浙江省农业科学院园艺研究所, 浙江杭州 310021;杭州千岛秀菇生物科技有限公司, 浙江淳安 311701;常山豪锋农业开发有限公司, 浙江常山 324200
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本文系统研究了绣球菌水提物对小鼠非特异性免疫功能及细胞免疫功能的影响.研究发现,绣球菌水提物300和600 mg·kg-1剂量灌胃给药15 d,对环磷酰胺诱导小鼠免疫下降具有一定的保护作用,可增强巨噬细胞的吞噬功能;体外试验结果表明,绣球菌水提物0.4和0.8 mg·mL-1单独或联合ConA(5μg·mL-1)用药均具有明显的促淋巴细胞增殖作用.上述结果表明,绣球菌水提物具有促进免疫功能的药效学作用.
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