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目的:观察术前区域动脉持续灌注化疗并栓塞治疗局部晚期乳腺癌的效果。方法:应用术前超选择区域动脉插管持续灌注化疗结合次要供血动脉栓塞的方案,经治Ⅲa,b 期乳腺癌患者9 例。结果:在治疗后的1 个月内取得良好效果,有效率达89 % (8/9) 。结论:局部晚期乳腺癌术前区域动脉持续灌注化疗配合次要供血动脉栓塞可有效提高术前化疗疗效,显著缩短疗程且毒副反应小、简便,值得推广应用。
OBJECTIVE: To observe the effect of continuous intra-arterial chemotherapy and embolization in the treatment of locally advanced breast cancer. METHODS: A preoperative superselective regional arterial catheter infusion chemotherapy combined with a secondary arterial embolization protocol was performed in 9 patients with stage IIIa and b breast cancer. RESULTS: Good results were obtained within 1 month after treatment, with an effective rate of 89% (8/9). Conclusion: Preoperative regional arterial continuous infusion chemotherapy combined with secondary arterial embolization in locally advanced breast cancer can effectively improve the efficacy of preoperative chemotherapy, significantly shorten the course of treatment, and the toxicity is small and simple. It is worthy of popularization and application.