花生四烯酸的酶氧化导致一大批在生物化学上重要的产物生成,它们中有前列腺素、凝血素、前列环素和白三烯,这些物质合称类二十碳烷,它们构成花生四烯酸的所谓阶形瀑布(Cascade)。这方面的工作者创造了这个专用名词是为了描绘从花生四烯酸衍生出来的一连串不断增加的化合物。类二十碳烷是一类极其有效的、普遍存在的、并且具有各种各样迷惑人的作用的化合物,其中许多有能引起兴趣的多种药理性质,并具有重要的药用潜力。大约五十年前,发现了前列腺素和有关的化合物。采用不适当的分析技术加上第二次世界大战的发生使前列腺素的研究工作推 Enzymatic oxidization of arachidonic acid leads to the production of a large number of biochemically important products, including prostaglandins, prothrombin, prostacyclin and leukotrienes, collectively referred to as eicosanoids, which constitute peanut tetra The so-called cascade of acid. Workers in this area have created this nomenclature to describe a series of ever-increasing compounds derived from arachidonic acid. Eicosanoids are a class of compounds that are extremely effective, ubiquitous and have a wide variety of deceptive effects, many of which have a variety of pharmacological properties of interest and have important pharmaceutical potential. About fifty years ago, prostaglandins and related compounds were found. Adopting inappropriate analytical techniques and the occurrence of World War II pushed prostaglandin research into practice