据报道,致命性药物反应的发生率在内科住院病人为0.1％,在外科住院病人为0.01％。在英国,4.3％的麻醉意外死亡和5.6％的麻醉意外脑损害与药物过敏有关。在澳大利亚,麻醉病人过敏反应的发生率为1/5000～25000,死亡率为3.4％。因此,麻醉医师有必要对有药物过敏反应史的病人作出术前评佔,寻找合理的处理方案,以降低危险程度。过敏综合征(包括瘙痒、红斑、面红、 It has been reported that the rate of fatal drug reactions was 0.1% in hospital inpatients and 0.01% in hospital inpatients. In the United Kingdom, 4.3% of the accidental death of anesthesia and 5.6% of accidental brain damage related to drug allergy. In Australia, the incidence of anaphylactic reactions in anesthetized patients is 1 in 5000 to 25000 with a mortality rate of 3.4%. Therefore, it is necessary for anesthesiologists to preoperatively appraise patients with a history of drug allergy and find a reasonable treatment plan to reduce the risk. Allergic syndrome (including itching, erythema, redness,