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目的探讨超声实时弹性成像技术在甲状腺良、恶性结节鉴别诊断中的价值。方法对74例甲状腺结节患者共96个结节的超声弹性图像进行分析,比较超声弹性成像评分法及应变率(strain ratio,SR)比值法对甲状腺良、恶性结节的诊断价值。结果组织病理证实96个结节中良性结节55个,恶性结节41个;超声弹性图像评分≥4分诊断恶性结节的敏感性、特异性、阳性预测值、阴性预测值、准确率分别为68.29%、90.91%、84.85%、79.37%、81.25%;SR比值法诊断甲状腺恶性结节的最佳界值为2.850,以SR≥2.850诊断甲状腺恶性结节的敏感性、特异性、阳性预测值、阴性预测值、准确率分别为80.49%,89.09%,84.62%,85.96%,85.42%,2种方法比较差异无统计学意义(P>0.05)。结论超声弹性成像评分法及SR比值法在甲状腺良、恶性结节鉴别诊断中均有重要价值。
Objective To investigate the value of real-time ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules. Methods The echocardiographic images of 96 nodules from 74 patients with thyroid nodules were analyzed. The diagnostic value of ultrasound elastography scoring method and strain ratio (SR) ratio in benign and malignant thyroid nodules were compared. Results Histopathology confirmed that there were 55 benign nodules and 41 malignant nodules in 96 nodules. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of ultrasonic elastography in diagnosing malignant nodules were 4 The sensitivity, specificity and positive predictive value of SR≥2.850 for the diagnosis of thyroid malignant nodules were 2.850 and 2.850, respectively, which were 68.29%, 90.91%, 84.85%, 79.37% and 81.25% There was no significant difference between the two methods (P> 0.05). The accuracy of the two methods were 80.49%, 89.09%, 84.62%, 85.96% and 85.42% respectively. Conclusion Ultrasound elastography scoring method and SR ratio method in the differential diagnosis of benign and malignant thyroid nodules are of great value.