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肺结核病人在短程化疗同时,分别予以活卡介苗和高压热灭活卡介苗作免疫治疗。疗程前后的免疫学检查结果表明,高压热灭活卡介苗对结核病人细胞免疫功能无明显影响。活卡介苗使病人T_3细胞、T_4+T_8-T_3值与单纯化疗组比有明显升高,T_4/T_8比值明显降低,淋巴细胞转化功能明显提高,能增强结核病人正常保护性免疫反应及延长反应时限,是一种很有前途的免疫治疗剂。
Tuberculosis patients in the short-term chemotherapy at the same time, were given live BCG and high-pressure heat-inactivated BCG for immunotherapy. The results of immunological tests before and after treatment showed that high-pressure heat-inactivated BCG had no significant effect on the cellular immune function of patients with tuberculosis. Live BCG could significantly increase the ratio of T_4 + T_8-T_3 in patients with T_3 cells and chemotherapy alone, significantly reduce the ratio of T_4 / T_8 and improve the function of lymphocyte transformation, enhance the normal protective immune response and prolong the response time , Is a promising immunotherapeutic agent.