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慢性结肠炎(临床简称慢结)的纤维结肠镜检出率为30—80％,活检病理诊断为84.9％。慢结的病变表现为慢性非特异性炎症,其病因众说不一尚无定论。临床上多数病例经抗感染治疗效果不佳,致使病情迁延难愈。目前倾向其为一多病因疾病,但有人经过前瞻性研究,仍有较多病例病因不明。炎症性肠病(Inflammatorybowel disease,IBD)包括克隆氏病,溃疡性结肠炎等也是一类病因未明的肠道炎症性疾病,目前认为免疫紊乱是发病的主要因素。为了解两个病间的关系和推断病因,我们对42例慢结和8例IBD进行了显微、超微观察和近三年的随访和总结。
Chronic colitis (clinical abbreviation slow knot) colonoscopy detection rate of 30-80%, biopsy pathological diagnosis was 84.9%. Slow knot lesions showed chronic nonspecific inflammation, the etiology of different opinions are not conclusive. Most cases of clinical anti-infective treatment ineffective, resulting in prolonged recovery refractory. At present it tends to be a multi-etiological disease, but some people have been prospectively studied and there are still many more etiologically unknown cases. Inflammatory bowel disease (IBD), including Crohn’s disease, ulcerative colitis, is also a type of inflammatory bowel disease of unknown etiology. It is currently considered that immune disorder is the main factor in the pathogenesis. To understand the relationship between the two diseases and to infer the etiology, we performed microscopic and ultramicroscopic observation of 42 chronic and 8 IBD patients and the follow-up and summary of the past three years.