Griffith在对百日咳菌苗情况的评论中,也许比较倾向于美国对这个问题的看法.尽管美国由于儿科专家的贡献而使百日咳菌苗接种维持在一个高水平上,但是对医生及菌苗制造者的起诉并不少见.百日咳菌苗脑病从未被令人满意地证实过,没有一项前瞻性研究证明两者的联系.人们并不怀疑百日咳全菌体菌苗会引起癫痫发作、低血压、发热、兴奋不安以及局部反应,问题在于它是否会引起永久性神经系统后遗症?作者认为,这种菌苗对易患儿 Griffith’s comments on pertussis vaccine may be more toward the United States ’perception of the problem, and although the United States has maintained a high level of pertussis vaccination because of pediatricians’ contributions, doctors and vaccine makers Prostatitis is not uncommon, and pertussis bacilli encephalopathy has never been satisfactorily confirmed, and no prospective study has proven the association between the two. One does not suspect that B. pertussis bacterins can cause seizures, hypotension, Fever, irritability and local reactions, the question is whether it will cause permanent neurological sequelae? The author believes that this vaccine for children with easy