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目的研究高龄老人黄斑区视网膜厚度的分布情况。方法采用频域光学相干断层扫描(SD-OCT)对62例(62只眼)80~90岁健康老人黄斑区视网膜进行扫描,依据系统默认的ETDRS分区,测量9个分区内厚度及内环(即0~3 mm直径区域)总厚度,测量区(即0~6 mm直径区域)总厚度,黄斑中心凹厚度。采用独立样本t检验比较性别、眼别之间的厚度差异;采用直线相关系数分析年龄与黄斑中心凹、黄斑中心区、内环总厚度、测量区总厚度之间的相关关系。结果右眼与左眼,男性右眼与左眼黄斑中心凹及各区域平均厚度比较差异无统计学意义(P>0.05)。男性与女性,女性右眼与左眼,男性与女性右眼黄斑中心凹及各区域平均厚度比较,除中心区差异有统计学意义(P<0.05),其余差异无统计学意义(P>0.05)。男性与女性左眼黄斑中心凹及各区域平均厚度比较,除内环下方区域差异有统计学意义(P<0.05),其余差异无统计学意义(P>0.05)。年龄与黄斑中心凹、黄斑中心区、内环总厚度、测量区总厚度之间无相关关系(P>0.05)。结论测量并研究高龄老人黄斑区视网膜厚度值的特点,可以为临床诊治该年龄段人群的黄斑疾病提供数值参考。
Objective To study the distribution of retina thickness in the elderly with macular area. Methods Sixty-two eyes (62 eyes) of macular retina of 80-90-year-old healthy people were scanned by frequency-domain optical coherence tomography (SD-OCT). According to the system default ETDRS subarea, Namely 0 ~ 3 mm diameter area) total thickness, the total thickness of the measurement area (ie, 0 ~ 6 mm diameter area), foveal thickness. The independent sample t-test was used to compare the differences in thickness between the sexes and eyes. The linear correlation coefficient was used to analyze the correlation between age and macular foveal, macular center, total inner ring thickness and the total thickness of the measurement area. Results There were no significant differences in the average thickness of the right and left eyes between the right eye and the left eye and the average thickness of each region (P> 0.05). There was no significant difference between the male and female, the right and left eyes of women, the right and left foveal thickness of men and women and the average thickness of each region except the central region (P <0.05) ). There were significant differences in the foveal macular fovea and the average thickness of each region between male and female, except for the region below the inner ring (P <0.05), while the other differences were not statistically significant (P> 0.05). Age and macular fovea, macular center, the total thickness of the inner ring, the total thickness of the measurement area was not related (P> 0.05). Conclusion The measurement and study of the macular retinal thickness in the elderly can provide a numerical reference for the diagnosis and treatment of macular degeneration in this age group.