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早期生长反应基因egr-1的生理功能愈来愈受到重视。其编码的蛋白质有3个重复的锌指结构域,属锌指蛋白家族,是一个转录因子,参与许多靶基因的表达调控。egr-1亦属即刻早期基因,可能介入外界信号与靶基因表达的偶联。
Physiological functions of early growth response gene egr-1 are gaining more and more attention. The encoded protein has three repeated zinc finger domains, belonging to the zinc finger protein family and is a transcription factor involved in the regulation of many target genes. Egr-1 is also an immediate early gene that may intervene in the coupling of external signals to target gene expression.