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甲氯灭酸盐是一种非类固醇类抗炎药物,本文评价该药物在治疗肾病综合征方面的效应,并对肾功能的药救也作了评价。按照下列标准选择病人进行治疗:1)组织学证实的局灶性节段性肾小球硬化症,膜性肾小球病或肾上腺皮质激素不敏感的微小病变的肾病综合征。2)血清白蛋白等于或少于1.5gm/dl,或者24小时尿蛋白排泄等于或大于8gm。3)血肌酐等于或小于3mg/dl。4)年龄大于18秒。5)无肝脏疾病或充血性心力衰竭。6)具有肾上腺皮质激素不敏感型的肾病综合征。
Meclofenamate is a non-steroidal anti-inflammatory drug, this article evaluates the effect of the drug in the treatment of nephrotic syndrome and also evaluates the efficacy of the drug in renal function. Patients are selected for treatment according to the following criteria: 1) Nephrotic syndrome with histologically-confirmed focal segmental glomerulosclerosis, membranous glomerulopathy or adrenocorticotensin-refractory minor lesions. 2) serum albumin equal to or less than 1.5 gm / dl, or 24-hour urinary protein excretion equal to or greater than 8 gm. 3) serum creatinine equal to or less than 3mg / dl. 4) is older than 18 seconds. 5) No liver disease or congestive heart failure. 6) with adrenal hormone-insensitive nephrotic syndrome.