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1986年2月4~7日在美国加利福尼亚州风景秀丽的Carmel同时召开了几个美国西、南部地区的临床研究学术年会。现仅摘录男性抗生育的可能途径部分报道如下: 发展一种安全有效的男性抗生育途径已迫在眉捷。在这次的Carmel会议上,几个研究组分别报道了使用GnRH类似物作为男性抗生育剂的可能性。例如,有的研究组给灵长类用一种GnRH的拮抗剂并配用睾酮可以有效地抑制精子生成,但仍维持血清睾酮于正常水平,从而为发展一种可用于男性且无明显副反应的抗生育途径提供了动物实验基础。Harbor-UCLA的Swerdloff等给正常男
1986 February 4 ~ 7 in the United States, California, the beautiful Carmel at the same time held a number of the United States western and southern clinical research academic annual meeting. The only available excerpts from men’s antifertility are reported below: It is urgent to develop a safe and effective male antifertility approach. At this Carmel conference, several study groups reported the possibility of using GnRH analogs as male anti-fertility agents, respectively. For example, some research groups give primate a GnRH antagonist with testosterone that effectively inhibits spermatogenesis but still maintains normal levels of serum testosterone, thereby providing a means of developing a side effect that can be used in men without significant side effects The anti-fertility pathway provides the basis of animal experiments. Swerdloff from Harbor-UCLA et al. Gave normal men