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观察了100例急性白血病患者血清中蛋白质、脂质结合唾液酸(LBSA)、脂蛋白和载脂蛋白的水平,发现初、复发组除LBSA明显升高外,Pr、TC、HDL-C、LDL-C、ApoA-1和ApoB均显著降低,尤以TC、HDL-C和ApoA-1下降幅度大。完全缓解组TC/Pr、LDL-C/Pr和ApoB/Pr明显高于未缓解组;外周白细胞总数>10×10~9/L组TC/Pr、LDL-C/Pr明显低于白细胞总数<10×10~9/L组,而两组Pr含量无显著差异。
The levels of serum protein, lipid-bound sialic acid (LBSA), lipoprotein and apolipoprotein in 100 patients with acute leukemia were observed. The levels of Pr, TC, HDL-C, LDL C, ApoA-1 and ApoB were significantly decreased, especially in TC, HDL-C and ApoA-1 decreased greatly. The levels of TC / Pr, LDL-C / Pr and ApoB / Pr in complete remission group were significantly higher than those in non-remission group. TC / Pr and LDL-C / Pr in peripheral leukocyte count> 10 × 10 ~ 10 × 10 ~ 9 / L group, but no significant difference between the two groups Pr content.