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既往对安体舒通治疗多毛效果的报道,大多根据主观评分,极少的几篇根据客观测量的研究却因毛的取样部位、药物剂量的不同以及毛干直径测量次数过少而得出矛盾的结果。本文采用了主客观综合评价方法,研究了安体舒通治疗多毛的效果。受试者为22名多毛妇女,年龄中位数32岁,2例闭经,11例周期不规则,9例周期规则,血清总睾酮中位数为2.9nmol/l,LH9.3IU/1。因各种原因禁用乙炔雌二醇及醋酸赛普龙周期疗法。安体舒通剂量为200mg/日,疗程为12个月,其中18名完成整个疗程。观察指标是:1)主观评分法。由
Previous reports of spironolactone treatment of hirsutism, mostly based on subjective scoring, rarely based on objective measurement of several studies but because of the wool sampling site, the difference in drug dosage and the number of measurements of hair shaft diameter is too small and contradictions the result of. In this paper, a comprehensive evaluation of subjective and objective methods to study the effect of spironolactone treatment of hairy. The subjects were 22 hirsutism women, with a median age of 32 years, two cases of amenorrhea, 11 cases of irregular cycle, 9 cases of periodic rules, the median serum total testosterone 2.9nmol / l, LH9.3IU / 1. Disable ethidium estradiol and cyclophilin cycle therapy for a variety of reasons. Spironolactone dose 200mg / day, treatment for 12 months, of which 18 to complete the entire course of treatment. Observations are: 1) subjective scoring method. by