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[目的]探讨鼻咽癌患者放疗前后不同时期的生存质量。[方法]采用患者自填的方式,对518例鼻咽癌患者应用中文版SF-36进行调查,利用信度分析和因子分析评价SF-36的信度及效度,利用方差分析比较鼻咽癌患者放疗前后不同时期生存质量在SF-36各领域的差异。[结果]鼻咽癌患者放疗前后不同时期的生存质量分析,社会功能、情感职能和精神健康三个领域以及总的健康变化等方面均有统计学意义(P<0.05)。放疗中患者的生存质量最低,放疗后患者随着生命时间延长,生存质量回升,甚者超过放疗前的生存质量。[结论]提示放疗前应加强患者的心理辅导,减轻其在治疗期间的心理负担。
[Objective] To investigate the quality of life of patients with nasopharyngeal carcinoma before and after radiotherapy. [Methods] A total of 518 patients with nasopharyngeal carcinoma undergoing self-management were enrolled in the study. SF-36 was evaluated using reliability analysis and factor analysis. The ANOVA was used to compare nasopharyngeal The difference of quality of life in different stages of cancer patients before and after radiotherapy in SF-36. [Results] There were significant differences in quality of life, social function, emotional function and mental health of patients with nasopharyngeal carcinoma before and after radiotherapy, as well as total health changes (P <0.05). The quality of life of radiotherapy patients is the lowest. After radiotherapy, the patients’ quality of life rises with the prolongation of life time, and the quality of life exceeds the quality of life before radiotherapy. [Conclusion] It is suggested that psychological counseling should be strengthened before radiotherapy to reduce their psychological burden during treatment.