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在体外可以观察到:二倍体细胞从一种细胞的表型转变成另一种细胞表型,这样的变化,主要与特殊细胞的特征和新分化后的机能表现有关。然而,单细胞起源的这种多态性细胞群,目前在生物化学方面尚未建立。来自杂合子女性肿瘤的分析表明:有些肿瘤是从单细胞演变而来,而另一些则可能
It has been observed in vitro that diploid cells are transformed from one cell phenotype to another cell phenotype and that such changes are primarily related to the characteristics of particular cells and the performance of the newly differentiated cells. However, this polymorphic population of single-cell origin is currently not biochemically established. Analysis of heterozygous female tumors suggests that some tumors evolved from single cells while others may