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目的探讨高龄初产对围生儿的影响。方法选取年龄在35~45岁的高龄初产产妇200例作为研究组,同时选取年龄<35岁的正常年龄初产产妇200例作为对照组,比较2组产妇的分娩方式及围生儿情况。结果研究组孕妇进行剖宫产的比例高于对照组孕妇,而进行自然分娩的比例低于对照组孕妇,差异均有统计学意义(P<0.05)。研究组200孕妇中,发生围生儿死亡8例(4.0%)、胎儿生长受限42例(21.0%),新生儿窒息40例(20.0%),新生儿畸形8例(4.0%);对照组患者中仅1例(0.5%)围生儿死亡,胎儿生长受限14例(7.0%),新生儿窒息5例(2.5%),新生儿畸形3例(1.5%)。研究组各种围生儿、胎儿及新生儿异常率均高于对照组,差异均有统计学意义(P<0.05)。结论高龄初产产妇不仅会影响分娩方式,还会对妊娠结局产生影响,使围生儿、胎儿或新生儿的异常率升高,在临床上应受到高度重视。
Objective To investigate the effect of early primipara on perinatal children. Methods 200 cases of aged primiparous women aged 35-45 years were selected as the research group. 200 normal-age primiparous women (age 35 years) were selected as the control group. The mode of delivery and perinatal conditions were compared between the two groups. Results The proportion of cesarean section in pregnant women in study group was higher than that in pregnant women in control group, while the proportion of spontaneous delivery in pregnant women in study group was lower than that in pregnant women in control group (P <0.05). Among the 200 pregnant women in the study group, 8 cases (4.0%) died of perinatal death, 42 cases (21.0%) had fetal growth restriction, 40 cases (20.0%) had neonatal asphyxia and 8 cases (4.0%) had neonatal asphyxia Only 1 (0.5%) of the patients in the group died of perinatal disease, 14 (7.0%) had fetal growth restriction, 5 (2.5%) neonatal asphyxia and 3 (1.5%) neonatal malformations. All cases of perinatal, fetal and neonatal abnormalities in the study group were higher than the control group, the difference was statistically significant (P <0.05). Conclusion The first trimester primiparae not only affects the mode of delivery, but also affects the outcome of pregnancy, and increases the abnormal rate of perinatal, fetal or neonatal. It should be highly valued clinically.