论文部分内容阅读
目的：为了探讨新生儿缺氧缺血性脑病（ＨＩＥ）时血清Ｔ３、ｒＴ３变化及临床意义。方法：是应用放射免疫法测定了新生儿缺氧缺血性脑病４０例和健康新生儿２６例血清Ｔ３和ｒＴ３值。结果：表明新生儿缺氧缺血性脑病患儿血清Ｔ３、ｒＴ３值与正常对照组比较有显著变化，血清Ｔ３、Ｔ３／ｒＴ３值与疾病的严重程度呈负相关，ｒＴ３值与疾病的严重程度呈正相关，特别是Ｔ３＜０．５ｎｇ／ｍｌ、Ｔ３／ｒＴ３值＜０．２５者，ｒＴ３＞４ｎｇ／ｍｌ者提示疾病危重，预后不良。结论：是血清Ｔ３、ｒＴ３的水平及Ｔ３／ｒＴ３的比值，可作为临床疾病严重程度和预后估计的指标之一。
Objective: To investigate the changes of serum T3 and rT3 in neonates with hypoxic-ischemic encephalopathy (HIE) and its clinical significance. Methods: Serum T3 and rT3 were measured by radioimmunoassay in 40 neonates with hypoxic-ischemic encephalopathy and 26 healthy neonates. Results: The serum T3, rT3 values of neonates with hypoxic-ischemic encephalopathy showed significant changes compared with the normal control group, serum T3, T3 / rT3 values and the severity of the disease was negatively correlated, rT3 value and the severity of the disease Positive correlation, especially T3 <0.5ng / ml, T3 / rT3 value of <0.25, rT3> 4ng / ml prompt disease critically ill, the prognosis is poor. Conclusions: Serum T3, rT3 levels and T3 / rT3 ratio can be used as one of the indicators of the severity of clinical disease and prognosis.