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临床上低血糖最常由药物引起,尤以胰岛素和磺脲类药物多见。采用胰岛素休克治疗精神病的措施已基本废除,作为药物副作用的低血糖症应尽可能避免产生。然而由于患者机体条件不同,如严格限制碳水化合物或垂体肾上腺功能不全;医生或患者对药物性能不够熟悉,某些药物扩展应用,如用胰岛素增进食欲治疗神经性厌食,用磺脲类药物特别是氯磺丙脲治疗真性尿崩症以及其他滥用药物等,致使药物性低血糖的发生率增加。其中伴有神志碍障或抽搐发作的严重类型低血糖也比较常见。现将除胰岛素以外的严重药物性低血糖有关问题综述如下。
Clinically, the most common cause of hypoglycemia drugs, especially insulin and sulfonylureas more common. Insulin shock treatment of mental illness has been basically abolished measures as a side effect of drugs hypoglycemia should be avoided as much as possible. However, due to the different conditions of the patient’s body, such as severe restrictions on carbohydrates or pituitary adrenal insufficiency; doctors or patients are not familiar with the performance of drugs, some drugs extended applications, such as the use of insulin to promote appetite for anorexia nervosa, with sulfonylureas, Chlorpromazine treatment of true diabetes insipidus and other drug abuse, resulting in increased incidence of drug-induced hypoglycemia. Serious types of hypoglycaemia associated with delirious or convulsive seizures are also common. Now in addition to other serious insulin-like hypoglycemia related issues are summarized below.