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非胰岛素依赖型糖尿病(NIDDM,Ⅱ型)在中老年相当常见,多因与靶细胞受体结合减少,胰岛素相对缺乏所致。由于病因各异,单一降糖药物疗效往往欠佳,且长期用药其继发性无效率(开始用药有效)每年可增加25％,联合用药常能有效控制病情,但应注意各药的适应证及剂量,否则可能产生严重的不良后果。我院曾收治1例应用苯乙双胍与消渴丸联合治疗Ⅱ型糖尿病而引起严重低血糖昏迷的病例,报告如下: 患者,男性,60岁,农民。Ⅱ型糖尿病史5年,原以六味地黄丸,消渴丸(10丸/次,1日3次)治疗,近来疗效不佳,症状反复不稳定。1994年8月11日某门
Non-insulin-dependent diabetes mellitus (NIDDM, type Ⅱ) is quite common in middle-aged and elderly people, mostly due to decreased binding to target cell receptors and the relative lack of insulin. Due to different causes, single antidiabetic drug efficacy is often poor, and long-term medication of its secondary inefficiency (effective start of medication) increased by 25% per year, the combination can often be effective in controlling the disease, but should pay attention to the indications of various drugs And the dose, otherwise it may have serious adverse consequences. In our hospital, one case of severe hypoglycemic coma caused by the combination of phenformin and Xiaoke Pill was treated in our hospital. The report was as follows: Patient, male, 60 years old, farmer. Type II diabetes history of 5 years, the original Liu Wei Di Huang Wan, Xiaoke Pills (10 pills / time, 3 times a day) treatment, the recent poor efficacy, symptoms repeatedly instability. A door on August 11, 1994