目的　探讨半乳糖凝集素Galectin 3(G 3)在脑星形胶质细胞瘤中的表达。以及与星形胶质细胞瘤WHO分级之间的关系。方法　应用免疫组化SP法检测 6 0例脑星形胶质细胞瘤标本中Galectin 3的表达 ,并检测不同的分级之间是否具有差异性。结果　Galectin 3的阳性率为 85 % ,随着肿瘤恶性程度增加 ,阳性细胞数目增加 ,不同WHO分级之间阳性表达率差异具有显著性。结论　Galectin 3在星形胶质细胞瘤中的阳性表达率与WHO分级有关 ,并可作为星形胶质细胞瘤恶性程度的重要分级指标。 Objective To investigate the expression of galectin 3 (G 3) in brain astrocytoma. As well as with the astrocytoma WHO classification relationship. Methods Immunohistochemical SP method was used to detect the expression of Galectin 3 in 60 samples of brain astrocytoma and to detect whether there is difference between different grades. Results The positive rate of Galectin 3 was 85%. As the degree of malignancy increased, the number of positive cells increased, and the positive rate of different WHO classification was significantly different. Conclusions The positive rate of Galectin 3 in astrocytomas is related to WHO classification and can be used as an important grading index for the degree of malignancy of astrocytoma.