目的探讨术前外周血单核细胞计数评估肾透明细胞癌患者预后的价值。方法收集156例肾透明细胞癌患者的临床病理资料,分析术前外周血单核细胞计数和临床病理特征与患者生存预后之间的相关性。结果单因素分析显示,年龄、TNM分期、肿瘤坏死、脉管侵犯和单核细胞计数均与肾透明细胞癌患者预后相关(P<0.05或P<0.01)。多因素分析表明,单核细胞计数和TNM分期是肾透明细胞癌患者的独立预后因素(P<0.05)。结论术前外周血单核细胞计数与肾透明细胞癌患者的预后密切相关,可作为预测肾透明细胞癌患者预后的有用指标。 Objective To investigate the value of preoperative peripheral blood mononuclear cell count in assessing the prognosis of patients with clear cell renal cell carcinoma. Methods The clinicopathological data of 156 patients with clear cell renal cell carcinoma were collected. The correlation between preoperative peripheral blood mononuclear cell count and clinicopathological features and prognosis of patients was analyzed. Results Univariate analysis showed that age, TNM stage, tumor necrosis, vascular invasion and monocyte count were all associated with the prognosis of patients with clear cell renal cell carcinoma (P <0.05 or P <0.01). Multivariate analysis showed that monocyte count and TNM stage were independent prognostic factors in patients with clear cell renal cell carcinoma (P <0.05). Conclusion Preoperative peripheral blood mononuclear cell count is closely related to the prognosis of patients with clear cell renal cell carcinoma and may be used as a useful indicator to predict the prognosis of patients with clear cell renal cell carcinoma.