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目的探讨前列地尔治疗腔隙性脑梗死患者的临床疗效,为临床治疗提供参考。方法选择2011年1月-2012年12月在我院进行治疗的78例腔隙性脑梗死患者做为观察对象,随机将78例患者分成两组,观察组与对照组,每组39例,对照组患者进行常规治疗,观察组患者在常规治疗的基础上应用前列地尔进行治疗,比较两组患者在治疗前后血压、血脂及血流变的变化。结果两组患者治疗前血压、血脂及血流变无明显差异(P>0.05),无统计学意义;观察组治疗后血压、血脂及血流变明显优于对照组(P<0.01),有统计学意义。结论前列地尔可明显改善腔隙性脑梗死患者的血压、血脂及血流变,临床疗效明显,故可在临床中推广应用。
Objective To investigate the clinical efficacy of alprostadil in the treatment of patients with lacunar infarction and provide a reference for clinical treatment. Methods 78 patients with lacunar infarction who were treated in our hospital from January 2011 to December 2012 were randomly divided into two groups: observation group (39 cases) and control group Patients in the control group were treated routinely. The patients in the observation group were treated with alprostadil on the basis of routine treatment. The changes of blood pressure, blood lipid and blood rheology were compared between the two groups before and after treatment. Results There were no significant differences in blood pressure, blood lipids and blood rheology between the two groups before treatment (P> 0.05), but the blood pressure, blood lipids and blood rheology in the observation group were significantly better than those in the control group (P <0.01) Statistical significance. Conclusion Alprostadil can significantly improve lacunar infarction patients with blood pressure, blood lipids and blood rheology, clinical efficacy significantly, it can be widely used in clinical practice.