目的:对酚妥拉明联合阿拉明治疗小儿肺炎合并心力衰竭做出临床疗效评价。方法:将100例患儿随机分为治疗组和对照组各50例,对照组入院后给予常规综合治疗,包括使用肾上腺皮质激素、镇静剂、强心(应用两地兰)、利尿、吸氧等药物治疗。治疗组在对照组基础上酚妥拉明0.5~1 mg/次,两药直接加入5%葡萄糖液50 ml内缓慢滴入。结果:治疗组显效36例,有效12例,无效2例,总有效率为96.0%;对照组显效24例,有效13例,无效13例,总有效率为74.0%。治疗组优于对照组,差异有统计学意义(P<0.05)。治疗组患儿心力衰竭控制时间、喘息症状消失时间、肺湿啰音消失时间及平均住院时间均明显少于对照组(P均<0.05);心肌酶水平值(CK-MB)差异有统计学意义,射血分数(EF)、E/A比较差异无统计学意义(P>0.05),两组均无明显不良反应。结论:酚妥拉明联合阿拉明治疗小儿肺炎合并心力衰竭临床效果好,不良反应少,值得进一步推广。 OBJECTIVE: To evaluate the clinical efficacy of phentolamine combined with alamin in the treatment of children with pneumonia complicated with heart failure. Methods: One hundred cases were randomly divided into treatment group (50 cases) and control group (50 cases). Patients in control group were given general treatment after admission, including adrenal cortex hormones, tranquilizers, medical treatement. The treatment group in the control group based on phentolamine 0.5 ~ 1 mg / time, two drugs directly into the 5% glucose solution 50 ml slowly dripped. Results: In the treatment group, 36 cases were markedly effective, 12 cases were effective, 2 cases were ineffective and the total effective rate was 96.0%. In the control group, 24 cases were markedly effective, 13 cases were effective and 13 cases were ineffective. The total effective rate was 74.0%. The treatment group was better than the control group, the difference was statistically significant (P <0.05). The time of heart failure control, the disappearance of wheezing symptoms, the disappearance of pulmonary dampness and the average length of hospital stay in the treatment group were significantly less than those in the control group (all P <0.05). There was a statistically significant difference in CK-MB between the two groups Significance, ejection fraction (EF), E / A was no significant difference (P> 0.05), no significant adverse reactions in both groups. Conclusion: Phentolamine combined with Alamin in children with pneumonia complicated with heart failure clinical effect is good, less adverse reactions, it is worth further promotion.