本研究旨在评价根尖周肉芽肿的细菌种类及对抗生素的敏感性。作者采用年龄为18～61岁的16名患者(男6、女10)的前牙,均无窦道或深牙周袋、并经根管充填、根尖周有明显阴影,且在3个月内未曾用抗生素治疗。在正常根尖切除术、根尖刮治术和根管逆充填术时无菌采集牙的根尖周肉芽肿。除常规切开、翻瓣、冲洗外,加用消毒吸引器头并用消毒刮匙去除一半肉芽肿,移入厌氧血肉汤中培养,另一半则经固定作组 The purpose of this study was to evaluate the bacterial species and the sensitivity to antibiotics in periapical granuloma. The authors used 16 patients (male 6, female 10) aged 18 to 61 years, anterior teeth, no sinus or deep periodontal pocket, and filling through the root canal, periapical obvious shadow, and in 3 No antibiotics were used during the month. Periapical granuloma was collected aseptically during normal apical resection, apical curettage, and root canal retrograde filling. In addition to conventional incision, flap, wash, plus disinfectant head and disinfection curette to remove half of granulomas, transferred to anaerobic blood broth culture, the other half is fixed as a group