现已知道,T细胞参与许多由抗原活化B细胞的调节反应,例如,大多数类型的T依赖性抗原诱导的抗体形成反应需要辅助性T细胞(T_H)的辅助。对于依赖T_H细胞的不同B细胞亚群的活化已知有两种途径。一种是Lyb5-B细胞的活化需受MHC约束 It is known that T cells are involved in many regulatory responses that activate B cells by antigens. For example, most types of T-dependent antigen-induced antibody-forming reactions require the assistance of helper T cells (T_H). There are two known ways of activating B cell subsets dependent on T-H cells. One is the activation of Lyb5-B cells subject to MHC constraints