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本文报导了1例急性原始淋巴细胞性白血病(ALL)患者伴有14q~+标记染色体的病例。经用分带技术作细胞遗传分析后证实,此染色体畸变不同于非淋巴细胞性白血病的类型。慢粒的Ph染色体为9:22易位,早幼粒患者的易位为15和17号染色体,淋巴瘤患者并发急性白血病时,常见有B组染色体缺失。而此例则为t(11;14)(q23;q32)。一33岁男性白人,1977年8月以发烧、盗汗、齿龈出血、咯血等及淋巴结、肝脾肿大而住院。当时白细胞数20,400/mm~3,其中原始淋巴细胞占42%,并有少量幼稚粒细胞及幼稚红细胞,骨髓活
This paper reports a case of a chromosome associated with 14q ~ + marker in 1 patient with acute lymphoblastic leukemia (ALL). The use of banding technology for cytogenetic analysis confirmed that this chromosomal aberration is different from the type of non-lymphocytic leukemia. Chromosome Ph chromosome 9:22 translocation, promyelocytic translocation in patients with chromosome 15 and 17, lymphoma patients with acute leukemia, the common group B chromosomal deletion. This example is t (11; 14) (q23; q32). A 33-year-old male white, in August 1977 with fever, night sweats, gum bleeding, hemoptysis, and lymph nodes, hepatosplenomegaly and hospitalization. At that time, the number of white blood cells 20,400 / mm ~ 3, of which 42% of primitive lymphocytes, and a small amount of immature granulocytes and naïve erythrocytes, bone marrow alive