普通变异型免疫缺陷病(CVID)Com-mon Variable Immunodeficiency Disease又名迟发型低丙种球蛋白血症:是儿童时期常见的原发性免疫缺陷病之一,现报道我们近年来发现的4例,以期引起重视。 病例介绍 例1 女,11岁(431811)83年2月确诊,主诉为不规则发热10年,反复呼吸道感染4年。既往史:生后3个月起反复高效、出血点及肝脾肿大,拟诊为“恶网”勒雪氏病。经强的松等治疗,热退、肝脾缩小。3岁时二腮腺肿大持续,曾拟诊为“结节病”,以后仍不时发生。4岁时发热、皮疹、红斑肿胀,拟诊“红斑狼疮”?皮肌炎。半月后消失。6岁后反复低热、咳嗽,疑为肺结核,抗痨治疗1年未愈,确诊为肺 Common variant of immunodeficiency disease (CVID) Com-mon Variable Immunodeficiency Disease, also known as delayed type hypogammaglobulinemia: is one of the common childhood primary immunodeficiency disease, are now reported in 4 cases we found in recent years, In order to attract attention. Case description 1 female, 11 years old (431811) 83 years in February confirmed the main complaint of irregular fever for 10 years, repeated respiratory infections for 4 years. Past history: 3 months after birth repeatedly efficient, bleeding and hepatosplenomegaly, to be diagnosed as “evil net” Le snow disease. After the treatment of prednisone, hot retreat, liver and spleen reduced. Parotid gland swelling at 3 years of age continued, had been diagnosed as “sarcoidosis”, still occur from time to time. 4 years old fever, rash, erythema swelling, to be diagnosed “lupus” dermatomyositis. After half a month disappeared. 6 years after repeated low fever, cough, suspected tuberculosis, anti-tuberculosis treatment for 1 year healed, diagnosed with lung