肠出血性大肠杆菌(EHEC)的某些株可产生Vero毒素1(VT1)和(或)2(VT2),这些细菌是人类和其它动物出血性或非出血性结肠炎的病因。此外在人类,它们还引起溶血性尿毒综合征和血栓性血小板减少性紫癜。据信Vreo毒素是这些综合征的毒性因子,但它们在疾病中的作用仍然不清。当毒素作用于HeLa或Vero细胞时可引起细胞裂解。悉生猪对实验感染EHEC非常敏感,已经被用作研究这些细菌致病性的模型。当产Vero毒素大肠杆菌接种悉生猪时产生非出 Certain strains of enterohemorrhagic Escherichia coli (EHEC) produce Vero toxin 1 (VT1) and / or 2 (VT2), which are the etiologies of hemorrhagic or non-hemorrhagic colitis in humans and other animals. In addition, in humans, they also cause hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Vreo toxin is believed to be a toxic factor in these syndromes, but their role in the disease remains unclear. When toxins act on HeLa or Vero cells can cause cell lysis. Swine pigs are very sensitive to experimentally infected EHEC and have been used as a model to study the pathogenicity of these bacteria. When producing Vero toxin Escherichia coli inoculated sire produce non-out