最近证实 ,蛋白酶抑制药 (ＰＩ)联用疗法对ＨＩＶ 1复制有显著而持久的抑制作用。然而 ,ＰＩ亦可导致明显代谢副作用如高血脂、外周脂肪消耗、中心性肥胖、高血糖、胰岛素抵抗及引发糖尿病。本文旨在检验血糖及血脂浓度与ＰＩ类药物的关系 ,并寻找引发高血糖、高血脂及脂肪代谢 It has recently been demonstrated that protease inhibitor (PI) combination therapy has a significant and sustained inhibitory effect on HIV 1 replication. However, PI can also cause significant metabolic side effects such as hyperlipidemia, peripheral fat loss, central obesity, hyperglycemia, insulin resistance, and diabetes mellitus. This article aims to test the relationship between blood glucose and lipid concentrations and PI drugs and to find triggers high blood sugar, high cholesterol and fat metabolism