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目的比较老年胃癌全胃切除术后早期肠内营养(EN)和肠外营养(PN)支持的效果。方法 51例老年胃癌全胃切除手术患者术后随机分为PN组(n=25)和EN组(n=26)。在营养支持前后检测氮平衡和营养指标,并观察两组患者住院时间和费用、肠道功能指标以及并发症发生情况。结果两组患者营养支持后,血清白蛋白、前白蛋白、转铁蛋白以及氮平衡4项指标升高,差异有统计学意义(P﹤0.05)。两组患者术后肛门排气时间、第一次排便时间、住院天数和日平均费用差异均有统计学意义,EN组显著低于PN组。两组患者术后无死亡或吻合口瘘等严重并发症。结论 EN能更好的改善患者术后营养状况和肠道功能,并且花费较低,优于PN。
Objective To compare the effects of early enteral nutrition (EN) and parenteral nutrition (PN) support after total gastrectomy for elderly patients with gastric cancer. Methods Fifty-one elderly patients with gastric cancer undergone total gastrectomy were randomly divided into PN group (n = 25) and EN group (n = 26). Nitrogen balance and nutritional indicators were measured before and after nutrition support, and hospitalization time and cost, gut function index and complication were observed. Results After nutritional support, serum albumin, prealbumin, transferrin and nitrogen balance increased in both groups, with statistical significance (P <0.05). There was significant difference between the two groups in the time of anal exhaust, the time of first defecation, the days of hospitalization and the average daily cost in EN group, which were significantly lower than those in PN group. No death or anastomotic fistula were found in the two groups after operation. Conclusions EN can better improve postoperative nutritional status and intestinal function, and cost less than PN.