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目的:了解盐城市盐都区新生儿出生缺陷发生率及顺位,探讨针对性的干预措施。方法:按照全国出生缺陷监测中心制定的监测方案,对2003～2008年盐都区围产期出生缺陷发生情况进行汇总分析。结果:2003～2008年平均出生缺陷发生率为4.67‰;出生缺陷前4位的依次是:总唇裂、指(趾)畸形、先天性心脏病、神经管畸形,分别占出生缺陷总例数的25.23%、12.61%、9.46%、8.56%;肉眼可见体表畸形缺陷儿占总例数的84.23%;出生缺陷产前诊断率为13.96%,产后诊断率为86.04%。结论:为减控出生缺陷,要大力开展全民性宣传倡导工作,强化出生缺陷一级干预措施的落实,建立高危人群监控信息库,通过培训、监测、质控,努力提高出生缺陷产前诊断率,减少出生缺陷在围产期特别是产前的漏诊。
Objective: To understand the incidence and the prevalence of neonatal birth defects in Yandu District of Yancheng City and to explore the targeted interventions. Methods: According to the monitoring plan developed by National Birth Defective Monitoring Center, the incidence of perinatal birth defects in Yandu District from 2003 to 2008 were summarized and analyzed. Results: The average incidence of birth defects from 2003 to 2008 was 4.67 ‰. The top four birth defects were: total cleft lip, digit deformity, congenital heart disease and neural tube defects, accounting for the total number of birth defects 25.23%, 12.61%, 9.46% and 8.56%, respectively. Gross body deformities accounted for 84.23% of the total cases. Birth defects were diagnosed prenatally at 13.96% and postpartum at 86.04%. Conclusion: In order to reduce birth defects, we must vigorously carry out advocacy work for all people to strengthen the implementation of a primary birth defects interventions, the establishment of high-risk population monitoring information base, through training, monitoring, quality control, efforts to improve the birth defects prenatal diagnosis rate , To reduce the birth defects in the perinatal period, especially missed prenatal diagnosis.