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采用放射免疫分析法观察了50例胃癌和20例胃溃疡患者的血清甲状腺激素变化,血清三碘甲状腺原氨酸(T_3),T_3/rT_3值均明显低于正常人;反三碘甲状腺原氨酸(rT_3),促甲状腺激素(TSH)均明显高于正常人;而甲状腺素(T_4)无明显变化.胃癌患者血清T_3,T_3/rT_3值和TSH明显低于胃溃疡患者,病情越严重,均值变化越明显.动态观察胃癌和胃溃疡患者甲状腺激素变化,有益于预测胃癌有无转移,胃溃疡有无恶变.
Radioimmunoassay was used to observe the changes of serum thyroid hormones in 50 cases of gastric cancer and 20 cases of gastric ulcer. Serum triiodothyronine (T_3) and T_3/rT_3 values were significantly lower than those of normal people; anti-triiododothyronine Acid (rT_3) and thyroid stimulating hormone (TSH) were significantly higher than those in normal subjects, but thyroid hormone (T_4) had no significant changes. The serum levels of T_3, T_3/rT_3, and TSH in gastric cancer patients were significantly lower than those in gastric ulcer patients. The more obvious the mean change, dynamic observation of gastric cancer and gastric ulcer patients with thyroid hormone changes, is helpful to predict whether there is metastasis of gastric cancer, gastric ulcer with or without malignant transformation.