以水杨基荧光酮为显色剂，确定了光度分析法同时测定钼、钨、锡、锑四组份的最佳条件。并采用迭代目标转换因子分析光度法，对地质样品中上述四组份进行了测定，测定结果的相对误差一般小于１０％ 。对浓度矩阵的实验设计、主因子数的确定、干扰及消除等问题进行了讨论 Using salicylfluorone as chromogenic reagent, the optimum conditions for simultaneous determination of four components of molybdenum, tungsten, tin and antimony by spectrophotometry were determined. The iterative target conversion factor spectrophotometry was used to determine the above four components in the geological samples. The relative error of the determination results was generally less than 10%. The experimental design of concentration matrix, the determination of the number of main factors, interference and elimination are discussed