用克拉玛依大沙鼠体内的利什曼原虫4个分离株接种一猴的皮下后,其中2个分离株使猴产生了皮肤利什曼病,利什曼原虫在猴的皮肤组织内可保持1年以上。另有一分离株接种至人的前臂皮下后128d,在接种部位产生了含虫的溃疡。从而证实当地大沙鼠体内的利什曼原虫能使人致皮肤利什曼病,推测鼠体内的利什曼原虫是当地人体皮肤利什曼病的病原。 After inoculation of a monkeys subcutaneously with 4 Leishmania isolates of Mus musculus large gerbil, 2 of the isolates gave the monkey a cutaneous leishmaniasis, and Leishmania maintained 1 in the monkey’s skin tissue Years or more. Another isolate was inoculated to human forearm subcutaneously 128d, resulting in the site of infection containing worms ulcer. Thus, it was confirmed that Leishmania domestica can cause leishmaniasis in human body. Leishmania in vivo is presumed to be the pathogen of local human leishmaniasis.