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目的旨在对慢性肾炎(CGN)患者踝臂指数(ABI)进行有效测量后,对其下肢外周动脉疾病(PAD)发生情况以及相关的危险因素进行客观性分析。方法对112例慢性肾炎患者结合踝臂指数测量数据分为PAD组(14例)和非PAD组(98例),并对两组研究资料予以血生化、心电图以及24h尿蛋白定量等相关内容检查。结果本组发生下肢外周动脉疾病者14例(12.5%)。两组患者在心肌梗死史、心肌缺血、间歇性破行、脑卒中发生率及舒张压、收缩压、24h尿蛋白定量等方面比较差异有统计学意义(P<0.05)。结论为了更好的预测慢性肾炎病患发生早期血管病变,应早期开展PAD的筛查工作。
Objective To objectively analyze the incidence of peripheral arterial disease (PAD) in lower extremities and related risk factors after effective measurement of ankle-brachial index (ABI) in patients with chronic nephritis (CGN). Methods 112 cases of chronic nephritis patients with ankle brachial index measurement data were divided into PAD group (14 cases) and non-PAD group (98 cases), and two groups of study data to be blood biochemistry, ECG and 24h urinary protein content and other related content check . Results In this group, 14 cases (12.5%) had peripheral arterial disease of the lower extremities. There was significant difference between the two groups in the history of myocardial infarction, myocardial ischemia, intermittent breaking, the incidence of stroke and diastolic blood pressure, systolic blood pressure and 24h urinary protein (P <0.05). Conclusion In order to better predict the occurrence of early vascular disease in patients with chronic nephritis, PAD screening should be carried out early.