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本临床试验旨在对广谱抗蠕虫药氟苯咪唑治疗钩虫、鞭虫、蛔虫病的疗效作出评价。作者于1978年7月在泰国南部对来自泰国南部春蓬府及其邻府农村地区的军人和军校青年学生共1,000人进行了检查。本组病人排除了再感染的因素。选择有钩虫、鞭虫、蛔虫感染的142例作临床试验。于早晨留取粪便标本,部分粪便于当天进行检查,其余的则保存于冷室内。患者体重48～70kg,年龄17～23岁,分两批进行治疗观察,第1批72例,第2批70例。于第2次服药时及服药后10～12小时由医生询问药物副反应。治疗前及治毕约4周用斯托尔氏法作虫卵计数,记录每克粪便虫卵数(EPG)。
The purpose of this clinical trial was to evaluate the efficacy of broad-spectrum anthelmintic flubendazole in the treatment of hookworm, whipworm and ascariasis. In July 1978, the author conducted inspections in southern Thailand on a total of 1,000 military and cadet young students from Chumphon Province, southern Thailand, and rural areas in neighboring countries. The group of patients ruled out the factors of re-infection. Choose hookworm, whipworm, roundworm infection of 142 cases for clinical trials. In the morning to take stool specimens, part of the stool in the day for inspection, while the rest is stored in a cold room. Patients weighing 48 ~ 70kg, aged 17 to 23 years old, were treated in two batches, the first batch of 72 cases, the second batch of 70 cases. In the second medication and medication after 10 to 12 hours by the doctor asked the drug side effects. Before treatment and about 4 weeks after treatment, Stoer’s method was used to count the number of eggs and record the number of fecal egg per gram (EPG).