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今年6月3～5日在美国华盛顿召开的百日咳菌苗会议传来讯息,百日咳无细胞菌苗接种3剂后预防百日咳的有效率为70％～90％,但其效果通常比全细胞菌苗差。欧洲的全细胞菌苗能提供最有效的保护作用,而美国的全细胞菌苗保护率较低。就无细胞菌苗而论,包含的组分越多,保护作用越佳。重组无细胞菌苗的有效接种剂量一般低于提纯的无细胞菌苗。无细胞菌苗引起的不良反应(如高热、局部反应)比全细胞菌苗少。
This year, June 3 to 5 in the United States held a meeting of pertussis vaccine came news, pertussis acellular cell vaccine inoculated three doses of prevention of whooping cough is 70% to 90%, but the effect is usually better than the whole cell vaccine difference. Whole-cell vaccine in Europe can provide the most effective protection, while the United States of America’s whole cell vaccine protection rate is low. In the case of cell-free bacterins, the more components contained, the better the protective effect. Effective vaccination doses of recombinant cell-free bacterins are generally lower than purified cell-free bacterins. Adverse reactions (such as hyperthermia, local reactions) caused by cell-free vaccine are less than those of whole cell vaccine.