我国人Rh 阴性率很低,抗D 抗体引起的溶血性输血反应很少见,但这一反应一旦发生,多很严重,能引起死亡。我们见过1例,报告如下。患者女性,34岁,已婚,汉族。1974年9月因甲状腺瘤复发住院。常规化验及肝、肾功能检查结果为:血红蛋白120g/L,二氧化碳结合力30mmol/L,血中非蛋白氮32.66mmol/L。9月17日针麻下行甲状腺瘤切除术,经过顺利。术前术中血压稳定为16/10.6kPa,输血460ml。回病房后发现伤口渗血较多,即返手术室拆除缝线检查伤口,并暂停输血。核查患者和供血者血型均为A 型无误,交叉配合无凝集。经局部压迫,注射6-氨基已酸和维生素K 后伤口渗血停止,重新缝合伤口,继续输血。术后3h 伤口又渗血,随后血压降至9/6.5kPa。经输血(200ml)滴注低分子右旋糖酐、碳酸氢 Rh-negative rate of our people is very low, anti-D antibodies caused by hemolytic transfusion reactions are rare, but the reaction occurred once more, very serious, can cause death. We have seen 1 case, the report is as follows. Patient female, 34 years old, married, Han nationality. September 1974 hospitalized for thyroid tumor recurrence. Routine laboratory tests and liver, kidney function test results: hemoglobin 120g / L, carbon dioxide binding 30mmol / L, blood non-protein nitrogen 32.66mmol / L. September 17 acupuncture underwent thyroidectomy, after a smooth. Preoperative intraoperative blood pressure was stable at 16 / 10.6kPa, transfusion 460ml. Back to the ward found that the wound bleeding more, that is, back to the operating room to remove the suture to check the wound, and suspended blood transfusion. Check the blood type of patients and donors were A type correct cross-co-coagulation. After local oppression, injection of 6-amino acid and vitamin K wound bleeding stopped, re-suture wounds, to continue blood transfusion. 3h after surgery wound bleeding, then blood pressure dropped to 9 / 6.5kPa. Transfusion (200ml) drip low molecular weight dextran, bicarbonate