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目的分析宫颈腺鳞癌的临床病理特征、诊治情况及影响预后的相关因素。方法回顾分析66例宫颈腺鳞癌患者的临床病理资料,随访其预后情况。结果宫颈腺鳞癌患者平均年龄(42.71±9.10)岁,病理分级以低分化居多(77.3%)。伴有术后高危病理因素者较不伴有高危病理因素的患者死亡率高(P<0.05)。多因素分析显示宫颈浸润间质深度是影响患者3年生存率及生存质量的独立因素(OR=3.215,P<0.05)。结论应重视腺鳞癌的诊治和随访。伴有高危病理因素者予以辅助放、化疗。
Objective To analyze the clinicopathological characteristics, diagnosis and treatment of cervical adenosquamous carcinoma and related factors that affect prognosis. Methods The clinical and pathological data of 66 cases of cervical adenosquamous carcinoma were retrospectively analyzed. The prognosis was followed up. Results The average age of patients with cervical adenosquamous carcinoma was (42.71 ± 9.10) years old, with poorly differentiated pathological grade (77.3%). Mortality was higher in patients with high-risk pathologic factors than those without high-risk pathologic factors (P <0.05). Multivariate analysis showed that the depth of cervical stromal invasion was an independent factor affecting the 3-year survival rate and quality of life (OR = 3.215, P <0.05). Conclusions Should pay attention to the diagnosis and treatment of adenosquamous carcinoma and follow-up. Associated with high-risk pathological factors to be assisted radiotherapy and chemotherapy.