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本文用放射配体法观察了维拉帕米(Ver)对恒河猴肾上皮细胞LDL受体活性的影响,发现Ver以浓度和时间依赖的方式明显增强受体介导的结合和内移过程,对降解的影响不显著。Ver作用浓度为44 mmol·L~(-1)效应最明显。
In this paper, the effect of verapamil on LDL receptor activity in rhesus monkey kidney epithelial cells was observed by radioligand method and found that Ver receptor significantly enhanced the receptor-mediated binding and internal migration process in a concentration- and time-dependent manner , The impact on degradation is insignificant. Ver effect concentration of 44 mmol·L -1 (-1) the most obvious effect.