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对35例药物性肝病(下称药肝)误诊原因进行分析。药肝占同期住院肝炎病人的1.5%其中黄疸型20例占同期因黄疸住院的1.1%。平均住院25±8d。ALT 好转显著较病毒性肝炎(下称病毒肝)快,血清胆红素消退显著较病毒肝慢。药物以避孕激素类(31.4%)、中药(28.6%)、抗高血压药类(11.4%)为多见。误诊原因为:①药物应用史遗漏(71.4%);②病毒肝史掩盖(17.1%);③对药肝认识不足;④“病毒性肝炎 HBsAg(-)××型”一词的滥用。对药肝诊断标准进行了探讨。
35 cases of drug-induced liver disease (hereinafter referred to drug liver) misdiagnosis of the reasons for analysis. Drug liver accounted for 1.5% of hospitalized patients with hepatitis in the same period, of which jaundice 20 cases accounted for 1.1% of hospitalized due to jaundice. The average hospitalization 25 ± 8d. ALT improved significantly more than viral hepatitis (hereinafter referred to as viral liver), serum bilirubin was significantly slower than the viral liver. Contraceptives drugs (31.4%), traditional Chinese medicine (28.6%), antihypertensive drugs (11.4%) are more common. The causes of misdiagnosis were: (1) the history of misdiagnosis of drug use (71.4%); (2) the cover of virus history of liver disease (17.1%); (3) the lack of understanding of drug liver; (4) the abuse of the term “viral hepatitis HBsAg (-) ×× type”. The diagnosis of drug-induced liver was discussed.