目的　研制复方前列腺炎栓剂及该栓剂的抑菌作用。方法　将黄柏等 9味中药采用水煎醇沉法制成栓剂 ,体外平皿抑菌法测定抑菌作用。结果　栓剂的外观、硬度、重量、融变时限均符合药典规定。对大肠杆菌、金黄色葡萄球菌、乙型溶血性链球菌的最低抑菌浓度分别是 12 .2 5 %、6 .2 5 %和 12 .2 5 % ,且随药物浓度增加 ,抑菌强度增加。结论　自拟方剂 ,制成栓剂 ,并通过抑菌、利尿、抗炎等实验 ,提示前列腺炎栓剂对前列腺炎有良好的治疗作用 ,为前列腺炎的临床药物治疗拓宽了途径 Objective To develop a compound prostatitis suppository and its antibacterial activity. Methods Nine Chinese herbs such as Phellodendron chinense (Cortex Phellodendri) were prepared into suppositories by decoction of alcohol and water, and the antibacterial activity was determined by antibacterial activity in vitro. Results suppository appearance, hardness, weight, melting time are in line with Pharmacopoeia regulations. The minimum inhibitory concentrations against Escherichia coli, Staphylococcus aureus and B hemolytic streptococcus were 12.5%, 6.52% and 12.5% ​​respectively. With the increase of the drug concentration, the antibacterial activity increased . Conclusion Self-made prescription, made of suppository, and through antibacterial, diuretic, anti-inflammatory and other experiments, suggesting that prostatitis suppository prostatitis has a good therapeutic effect for prostatitis clinical drug treatment to broaden the way