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我院儿科自1991年3月～1995年3月遇到皮试阴性的青霉素过敏反应23例,男17例,女6例;年龄3个月～1岁3例,～3岁2例,～7岁5例,～12岁13例。原发病为呼吸道感染21例,皮肤疖痈、淋巴结炎各1例。以上患儿皆无应用青霉素史,20例有药物、食物及其它过敏病史。青霉素皮试液的配制按护理学要求配成每0.1ml含青霉素50U的浓度。过敏反应多发生在用药后20～30分钟,3例在用药后2～5分钟即出现面色苍白、多汗、呼吸困难、血压下降等休克症状,4例在注射局部出现大面积风团,16例全身荨麻疹。一旦发现过敏反应立
Pediatrics in our hospital from March 1991 to March 1995 met skin test-negative penicillin allergic reactions in 23 cases, 17 males and 6 females; aged 3 months to 1 year in 3 cases, ~ 3 years in 2 cases, ~ 5 cases at 7 years old and 13 cases at ~ 12 years old. The primary disease was respiratory tract infection in 21 cases, skin 疖 痈, lymphadenitis in 1 case. None of the above children have a history of penicillin, 20 patients have a history of drugs, food and other allergies. Preparation of penicillin skin test solution according to the requirements of nursing each 0.1ml containing penicillin concentration of 50U. Allergic reactions occurred in the medication 20 to 30 minutes, 3 cases 2 to 5 minutes after treatment, pale, sweating, dyspnea, hypotension and other symptoms of shock, 4 cases in the injection of local large area wind group, 16 Whole body urticaria. Once found allergic stand