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目的：分析喉显镜手术中预注右旋美托咪啶的应用效果。方法随机选取2012年6月-2013年6月在我院实施喉显镜手术的68例患者，并将其平均分成两组，两组患者均采用雷米芬太尼和丙泊酚进行麻醉，其中在麻醉之前，对照组患者进行10ml的脂肪乳安慰剂的的静脉注射；观察组患者进行0.6 g/kg右旋美托咪啶。最后对患者在（T0）麻醉前、（T1）插管时、（T2）支撑喉镜置入时、（T3）拔管1分钟后和(T4)5分钟的NE(去甲肾上腺素)、HR以及丙泊酚用量等情况进行测定与记录。结果对照组HR、MAP以及血浆E与NE的浓度都呈明显降低现象，两组相比，差异显著，存在统计学意义（P<0.05）；对照组患者的丙泊酚用量为130±25mg,观察组患者为210±30mg，两组差异相比，差异明显，具有统计学意义（P<0.05）。结论在喉显镜手术中预注右旋美托咪啶，可以对患者的应激反应进行有效的减轻，值得推广。“,”application analysis of laryngeal microscope operation in the pre infusion of dexmedetomidine. Methods 68 cases were randomly selected in 2012 June -2013 year in June in our hospital implementation of laryngeal microscope operation patients, which were divided into two groups, two groups of patients with remifentanil and propofol in anesthesia, the patients in control group before, 10ml fat emulsion for intravenous injection of placebo; the patients in observation group were 0.6g/kg dexmedetomidine. At the end of the patients (T0) (T1) before anesthesia, intubation, laryngoscope (T2) placement (T3), extubation after 1 minutes and 5 minutes (T4) NE (norepinephrine), HR and the dosage of propofol were measured and recorded. Results in the control group, HR, MAP and plasma E and NE concentrations were significantly reduced, compared to the two groups, significant difference, there were statistical significance (P<0.05); the control group patients with propofol dosage was 130±25mg, the patients in observation group was 210 ± 30mg, compared, differences between the two groups differed significantly, with statistical significance (P<0.05). Conclusion in laryngeal microscope operation in the pre injection of dexmedetomidine on stress response of patients, can effectively reduce, worthy of promotion.