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目的观察更昔洛韦联合安达芬乳膏治疗带状疱疹的临床疗效和不良反应。方法带状疱疹患者150例随机分为治疗组与对照组。对照组70例予更昔洛韦0.2g静脉滴注,1次/d;甲钴胺片0.5mg,3次/d;维生素B110mg,3次/d。治疗组80例在此基础上加用安达芬乳膏4次/d。2组均连用7d。结果治疗组的平均止痛、止疱、结痂时间均短于对照组(P均<0.01),治疗组与对照组治疗有效率比较差异有统计学意义(96.2%vs68.6%,P<0.05)。结论安达芬乳膏联合更昔洛韦治疗带状疱疹疗效明显优于单用更昔洛韦。
Objective To observe the clinical efficacy and side effects of ganciclovir combined with Andamiflu cream in the treatment of herpes zoster. Methods 150 cases of shingles were randomly divided into treatment group and control group. Control group of 70 patients given ganciclovir 0.2g intravenous infusion, 1 / d; mecobalamin 0.5mg, 3 times / d; vitamin B1 10mg, 3 times / d. Treatment group, 80 cases on this basis with Andadfen cream 4 times / d. 2 groups were used in conjunction with 7d. Results The average analgesic, blister and scab time in the treatment group were shorter than those in the control group (P <0.01), and there was significant difference between the treatment group and the control group (96.2% vs68.6%, P <0.05 ). Conclusion Andadvan cream combined with ganciclovir treatment of herpes zoster was significantly better than with ganciclovir alone.